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US 11,589,807 B2Granted
Biosensor for monitoring eyedrop usage compliance
AssigneeThe Regents of the University of California
InventorJohn Liu
Life of this patent
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Abstract
Systems and methods for monitoring eyedrop usage are disclosed. Example embodiments include a system to monitor eyedrop usage. The system may include a detection and activation circuit couplable to a wireless biosensor and an eyedrop dispenser. The detection and activation circuit may include a pressure transducer that transmits a signal upon detecting a force at, or above, a threshold value. The system may also include a wireless biosensor insertable into a region of an eyelid. The wireless biosensor may include a sensor to detect the physical change and the chemical change of tears as a result of eyedrop usage. The wireless biosensor may also include a transceiver to receive the signal that activates the sensor for an activation time.
Claims20
A system to monitor eyedrop usage, the system comprising:
- an external detection and activation circuit couplable to an external eyedrop dispenser and configured to wirelessly communicate with a wireless biosensor, the external detection and activation circuit comprising:
- a pressure transducer configured to detect a force applied to the external eyedrop dispenser, wherein a signal to activate the wireless biosensor is transmitted in response to detecting the force at, or above, a threshold value, and
- the wireless biosensor insertable into a region of an eyelid, the wireless biosensor comprising:
- a power supply configured to power at least a transceiver and a sensor;
- the transceiver configured to wirelessly receive the signal from the external detection and activation circuit, wherein the transceiver is configured to, in response to wirelessly receiving the signal, activate the power supply to power the sensor for an activation time, and wherein the transceiver is configured to, in response to wirelessly receiving the signal, activate the sensor for the activation time;
- and
- the sensor configured to detect a chemical change of the eye in response to usage of the external eyedrop dispenser;
- and
- wherein the wireless biosensor goes into a sleep mode after the activation time, wherein the sleep mode comprises powering off the sensor.
6 more elements
A method comprising:
- coupling an external detection and activation circuit to an external eyedrop dispenser, wherein the external detection and activation circuit is configured to wirelessly communicate with a wireless biosensor, and wherein the external detection and activation circuit comprises:
- a pressure transducer configured to detect a force applied to the external eyedrop dispenser, wherein a signal to activate the wireless biosensor is transmitted in response to detecting the force at, or above, a threshold value, and;
- inserting the wireless biosensor into an eyelid, wherein the wireless biosensor comprises:
- a power supply configured to power at least a transceiver and a sensor;
- the transceiver configured to wirelessly receive the signal from the external detection and activation circuit;
- the sensor configured to detect a chemical change of an eye in response to usage of the external eyedrop dispenser;
- detecting the force at, or above, the threshold value using the pressure transducer;
- wirelessly receiving the signal at the transceiver;
- activating the power supply to power the sensor for an activation time
- activating the sensor for the activation time;
- during the activation time, dispensing eyedrops from the external eyedrop dispenser on a surface of an eye;
- responsive to activating the sensor for the activation time, detecting the chemical change to the eye as the result of the eyedrop usage during the activation time;
- and
- going into a sleep mode, wherein the sleep mode comprises powering off the sensor.
11 more elements
A system to monitor eyedrop usage, the system comprising:
- a wireless biosensor insertable into a region of an eyelid, wherein the wireless biosensor comprises:
- a power supply configured to power at least a transceiver and a sensor;
- the sensor configured to detect a chemical change of an eye in response to usage of an external eyedrop dispenser;
- and
- the transceiver configured to receive a signal from a n external detection and activation circuit, wherein the transceiver is configured to, in response to receiving the signal, activate the power supply to power the sensor for an activation time, and wherein the transceiver is configured to, in response to wirelessly receiving the signal, activate the sensor for the activation time, wherein the external detection and activation circuit, coupled to an external eyedrop dispenser, comprises a pressure transducer detecting a force applied to the external eyedrop dispenser, wherein the signal to activate the wireless biosensor is transmitted upon detecting the force at, or above, a threshold value;
- and
- wherein the wireless biosensor goes into a sleep mode after the activation time, wherein the sleep mode comprises powering off the sensor.
4 more elements
Dependencies are inferred from the claim text.