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US 11,589,785 B2Granted
Levodopa sensor for tight tuning of dosage
AssigneeMedtronic, Inc.
InventorsDavid Probst, Randal Schulhauser, Patrick W. Kinzie, Jadin C. Jackson, Daniel Hahn
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Abstract
An enzymatic sensor configured to determine the concentration of levodopa present in a sample according to a current or a resonant frequency produced in response to levodopa interactions with L-amino acid decarboxylase present in the sensor. A processor associated with the sensor determines levodopa concentration and produces dose recommendation or output according to levodopa concentration.
Claims10
A levodopa sensor device comprising:
- a processor;
- a polyimide pad layer with encapsulated L-amino acid decarboxylase;
- a harmonic oscillating circuit associated with the polyimide pad layer such that an electrochemical signal produced by interactions of a sample with the encapsulated L-amino acid decarboxylase will produce a resonant frequency on the circuit;
- and
- a computer-readable program code having instructions, which when executed cause the processor to:
- detect the resonant frequency obtained from the circuit;
- and
- compute a levodopa concentration based upon the resonant frequency obtained from the circuit.
5 more elements
Dependencies are inferred from the claim text.