Compositions and methods for transport and preservation of biological material
AssigneeAmericord Registry LLC
InventorsAndrew L'Huillier, Ayanna Bryan, Martin Smithmyer
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Abstract
Compositions and methods for the shipping, packaging, and freezing of whole or partial biological materials including but not limited to cells, tissues, and organs, designed to simultaneously reduce freezing damage and maintain tissue structure. The compositions include a buffered hyperosmotic solution, an oncotic agent, an antioxidant, a metal chelator, and a ketone body. These aspects of the present invention are applicable to transport and preservation of biological materials including but not limited to amniotic membrane of the placenta and umbilical cord and are applicable to preservation of cellular and acellular biological materials generally.
Claims17
A composition for the transport of biological material, comprising:
- a buffered hyperosmotic solution;
- an oncotic agent;
- an antioxidant;
- a metal chelator;
- and
- a ketone body.
A cryoprotectant composition for the cryogenic freezing and storage of live biological material, comprising:
- a buffered hyperosmotic solution;
- a polymer;
- an oncotic agent;
- an antioxidant;
- a metal chelator;
- and a ketone body.
Dependencies are inferred from the claim text.