2,2,2-trifluoroacetic acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl)methylene] method of making the same
AssigneeAbrexa Pharmaceuticals, Inc.
InventorsMichael O'Neill, Barbara Kidon, William A. Janz, Hongqiao Wu
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Abstract
Crystalline polymorph forms of neurotrophic agent 2,2,2-trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide (J147), and process for producing the crystalline polymorphic form are provided.
Claims15
An isolated crystalline Form II of 2,2,2-trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide (J147), having a powder X-ray diffraction pattern comprising peaks located at 13.37, 18.47, and 23.34+/−0.2 degrees 2-theta.
An isolated crystalline Form I of 2,2,2-trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide (J147), having a powder X-ray diffraction pattern comprising peaks located at 11.85, 17.11, 17.79, and 23.40+/−0.2 degrees 2-theta.
Dependencies are inferred from the claim text.