Back to results
US 11,583,860 B2Granted
Microstructured thin hydrogel films
AssigneeEcole Polytechnique Federale De Lausanne (Epfl)
InventorsSylke Höhnel, Nathalie Brandenberg, Matthias Lutolf
Life of this patent
Estimating the term…
Abstract
A device for aggregating cells includes a cavity. The cavity includes a plurality of microwells for receiving at least one cell. Each of the microwells includes a vertical sidewall and a curved bottom. The microwells are made in a hydrogel layer. Each of said microwells has a diameter and an interwell distance between one microwell and another microwell, wherein a ratio for the interwell distance to the diameter is less than or equal to 1/10.
Claims19
A device for aggregating cells, comprising:
- a cavity,
- wherein said cavity comprises a plurality of microwells for receiving at least one cell,
- wherein each of said microwells comprises a vertical sidewall and a curved bottom,
- wherein said microwells are made in a hydrogel layer,
- wherein each of said microwells comprises a height of 200 μm to 3 mm,
- wherein each of said microwells further comprises a diameter and an interwell distance between one microwell and another microwell,
- wherein a ratio for said interwell distance to said diameter is less than or equal to 1/10, and
- wherein said diameter of each of said microwells is 1 μm to 3 mm.
5 more elements
A device for aggregating cells, comprising:
- a plurality of cavities;
- a hydrogel layer;
- and
- a plurality of microwells disposed in each of the plurality of cavities, the plurality of microwells each configured to receive a cell, the plurality of microwells each comprising:
- a vertical sidewall;
- and
- a curved bottom,
- wherein each of the plurality of microwells has a diameter, a height and an inter-well distance between one microwell and another microwell which are configured independently from each other,
- wherein said plurality of microwells are made in said hydrogel layer,
- wherein a ratio for said interwell distance to said diameter is less than or equal to 1/10, and
- wherein said diameter of each of said microwells is 1 μm to 3 mm.
8 more elements
Dependencies are inferred from the claim text.