Back to results
US 11,577,241 B2Granted
Acoustofluidic systems including acoustic wave generators for manipulating fluids, droplets, and micro/nano objects within a fluid suspension and related methods
AssigneeDuke University
InventorsTony Jun Huang, Peiran Zhang
Life of this patent
Estimating the term…
Abstract
Acoustofluidic systems including acoustic wave generators for manipulating fluids, droplets, and micro/nano objects within a fluid suspension and related methods are disclosed herein. According to an aspect, an acoustofluidic system includes a substrate including a substrate surface. The system also includes an acoustic wave generator configured to generate acoustic streaming within an acoustic wave region of the substrate surface. Further, the acoustic wave generator is controllable to change the acoustic streaming for movement of a droplet or other micro/nano object on a fluid suspension about the acoustic wave region.
Claims28
An acoustofluidic system comprising:
- a substrate including a substrate surface;
- a plurality of first acoustic wave generators configured to generate acoustic streaming within acoustic wave regions of the substrate surface for movement of one or more droplets or micro/nano objects along a first direction;
- a plurality of second acoustic wave generators configured to generate acoustic streaming within acoustic wave regions of the substrate surface for movement of the one or more droplets or micro/nano objects along a second direction, different than the first direction;
- and
- a controller configured to input different amplitudes, frequencies, or phases into the plurality of first acoustic wave generators and the plurality of second acoustic wave generators to generate acoustic streaming.
2 more elements
An acoustofluidic system comprising:
- a substrate including a substrate surface;
- a plurality of first acoustic wave generators configured to generate acoustic streaming within acoustic wave regions of the substrate surface for movement of one or more droplets or micro/nano objects along a first direction;
- a plurality of second acoustic wave generators configured to generate acoustic streaming within acoustic wave regions of the substrate surface for movement of the one or more droplets or micro/nano objects along a second direction, different than the first direction;
- and
- a controller configured to controllably input a first excitation amplitude or a second excitation amplitude into each of the plurality of first acoustic wave generators and the plurality of second acoustic wave generators to move the one or more droplets or other micro/nano objects in either the first direction or the second direction.
2 more elements
An acoustofluidic system comprising:
- a plurality of first acoustofluidic wave generators configured to generate acoustic streaming within acoustic wave regions for movement of one or more droplets or micro/nano objects along a first direction;
- a plurality of second acoustic wave generators configured to generate acoustic streaming within acoustic wave regions of the substrate surface for movement of the one or more droplets or micro/nano objects along a second direction, different than the first direction;
- a structural feature having a shape to manipulate movement of a droplet or other micro/nano object;
- and
- a controller configured to control the plurality of first acoustic wave generators and the plurality of second acoustic wave generators to move the droplet or other micro/nano object towards the structural feature to manipulate movement of the droplet or other micro/nano object.
2 more elements
A method comprising:
- providing an acoustofluidic system comprising:
- a plurality of first acoustic wave generators configured to generate acoustic streaming within acoustic wave regions of a substrate surface for movement of one or more droplets or micro/nano objects along a first direction;
- a plurality of second acoustic wave generators configured to generate acoustic streaming within acoustic wave regions of the substrate surface for movement of the one or more droplets or micro/nano objects along a second direction, different than the first direction;
- and
- a controller configured to input different electrical signals into the plurality of first acoustic wave generators and the plurality of second acoustic wave generators to generate acoustic streaming;
- and
- using the controller to input the different electrical signals into the plurality of first acoustic wave generators and the plurality of second acoustic wave generators to generate acoustic streaming within acoustic wave regions for movement of the one or more droplets or micro/nano objects along the first direction or the second direction.
4 more elements
An acoustofluidic system comprising:
- a substrate including a substrate surface;
- and
- a dual-mode acoustic transducer controlled by a controller configured to manipulate droplets, cells, micro/nano particles or other micro/nano objects within the acoustic wave region, wherein the transducer is operable in a first mode for moving an object or particle along a top surface of the substrate in one direction, and wherein the transducer is operable in a second mode for moving the object or particle along the top surface over the substrate in another direction.
Dependencies are inferred from the claim text.