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US 11,564,394 B2Granted
Distorted gold (I)-phosphine complexes and and methods for use as antifungal agents
AssigneeUniversity of Kentucky Research Foundation
InventorsSylvie Garneau-Tsodikova, Emily K Dennis, Jong Hyun Kim, Samuel G. Awuah
Life of this patent
Estimating the term…
Abstract
The presently-disclosed subject matter describes distorted gold (I) phosphine compounds. The presently-disclosed subject matter also describes a method for killing fungus comprising contacting fungus with distorted gold (I) phosphine compounds. The presently-disclosed subject matter further describes a method of preventing or disrupting a biofilm on a surface comprising contacting a surface with distorted gold (I) phosphine compounds.
Claims16
A method for killing fungus comprising:
- contacting the fungus with an effective amount of a compound selected from the group consisting of:
- or a pharmaceutically acceptable salt thereof.
A method of preventing or disrupting a fungal biofilm comprising:
- contacting a surface with an effective amount of a compound selected from the group consisting of:
- or a pharmaceutically acceptable salt thereof;
- and wherein the surface is at risk of forming a biofilm or has a pre-formed biofilm.
Dependencies are inferred from the claim text.