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US 11,560,426 B2Granted
Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders
AssigneeAvenCell Europe GmbH
InventorArmin Ehninger
Life of this patent
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Abstract
The present invention relates to a targeting module comprising a chemically synthesized peptide binding moiety specific for a human cell surface protein or protein complex, a kit comprising the targeting module and a vector or a cell comprising a nucleic acid encoding a universal chimeric antigen receptor and the use for the treatment of cancer, infections and autoimmune disorders.
Claims12
A targeting module comprising:
- a glutamate-urea-lysine motif,
- a chelator, and
- a tag, wherein the tag comprises a human nuclear La protein epitope selected from SEQ ID NOs:
- 25 and 27.
1 more element
Dependencies are inferred from the claim text.