Back to results
US 11,559,785 B2Granted
Method for separation of radioactive sample using monolithic body on microfluidic chip
AssigneeUniversity of Hull
InventorsStephen James Archibald, Ping He, Stephen John Haswell, Nicole Pamme, Nathan Joel Brown, Mark Duncan Tarn, Richard Alexander, Mohammad Mehdi Nasr Esfahani
Life of this patent
Estimating the term…
Abstract
The present invention relates to monolithic bodies, uses thereof and processes for the preparation thereof. Certain embodiments of the present invention relate to the use of a monolithic body in the preparation of a radioactive substance, for example a radiopharmaceutical, as part of a microfluidic flow system and a process for the preparation of such a monolithic body.
Claims20
A process for separating an analyte from a radioactive sample, comprising:
- eluting the radioactive sample comprising the analyte through a chromatographic monolithic body, wherein:
- the chromatographic monolithic body is hermetically sealed within a polymer housing;
- the polymer housing comprises an inlet and an outlet and is prepared by molding a polymer around the chromatographic monolithic body;
- the chromatographic monolithic body, inside of the housing, is incorporated onto a surface of a microfluidic chip;
- the chromatographic monolithic body is selected from an inorganic monolithic body comprising functionalized silica and a normal phase monolithic body;
- and
- the microfluidic chip is part of a microfluidic flow system.
4 more elements
Dependencies are inferred from the claim text.