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US 11,555,213 B2Granted
Nucleic acid encoding a modified homoserine dehydrogenase
AssigneeCj Cheiljedang Corporation
InventorsHyo Jin Kim, Lan Huh, Sang Jo Lim, Hyun Ah Kim, Hyoung Joon Kim, Chang il Seo, Seung Bin Lee, Ji Sun Lee
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Abstract
The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.
Claims2
A polynucleotide encoding a modified homoserine dehydrogenase having at least 95% sequence identity with the polypeptide of SEQ ID NO:
- 1, wherein said modified homoserine dehydrogenase comprises an isoleucine at the position corresponding to position 285 of the polypeptide of SEQ ID NO:
- 1, and/or a glutamine at the position corresponding to position 398 of the polypeptide of SEQ ID NO:
- 1, and wherein the modified homoserine dehydrogenase has homoserine dehydrogenase activity.
Dependencies are inferred from the claim text.