Neurosteroid compounds and methods for their preparation and use in treating central nervous system disorders
AssigneeThe Texas A&M University System
InventorDoodipala Samba Reddy
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Abstract
Described herein is the chemical structure of neurosteroid derivative compounds, methods of synthesizing the derivatives, and their uses in treating disorders, including those of the central nervous system. These compounds are readily synthesized and have improved pharmaceutical properties, including water solubility, compared to known neurosteroids.
Claims16
A method for treating epilepsy comprising administering to a subject in need thereof a therapeutically effective amount of a compound, a pharmaceutically acceptable salt of said compound, or a pharmaceutical composition comprising a pharmaceutically acceptable excipient and said compound, said compound or said pharmaceutically acceptable salt being selected from:
A method for treating epilepsy comprising administering to a subject in need thereof a therapeutically effective amount of a compound, a pharmaceutically acceptable salt of said compound, or a pharmaceutical composition comprising a pharmaceutically acceptable excipient and said compound, said compound or pharmaceutically acceptable salt being selected from:
Dependencies are inferred from the claim text.