Systems and methods for scatter correction of image

A system, comprising:

• at least one storage device including a set of instructions for scatter correction of an image;
• and
• at least one processor configured to communicate with the at least one storage device, wherein when executing the set of instructions, the at least one processor is configured to direct the system to:
• obtain an image of a subject, the image being generated by operating an X-ray imaging device to perform a first scan on the subject;
• obtain a reference image of air, the reference image being generated by operating the X-ray imaging device to perform a second scan on the air;
• identify an object of interest (OOI) from the image, the OOI including one or more pixels;
• for each pixel of the one or more pixels of the OOI,
• determine, based on a pixel value of the each pixel and the reference image, an equivalent thickness of the OOI corresponding to the each pixel, the equivalent thickness of the OOI corresponding to the pixel being a travelling distance of radiation photon(s) corresponding to the pixel through the subject;
• determine a scatter correction coefficient of the each pixel based at least in part on the equivalent thickness of the OOI corresponding to the each pixel;
• and
• correct the pixel value of the each pixel using the corresponding scatter correction coefficient.