Kit, device and method for detecting prostate cancer
AssigneesToray Industries, Inc., National Cancer Center
InventorsMakiko Yoshimoto, Hiroko Sudo, Atsuko Miyano, Satoko Kozono, Takahiro Ochiya, Hiroyuki Fujimoto, Fumihiko Urabe, Juntaro Matsuzaki
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Abstract
This invention provides a kit or device for detection of prostate cancer and a method for detecting prostate cancer. This invention provides a kit or device for detection of prostate cancer comprising a nucleic acid capable of specifically binding to an miRNA in a sample from a subject or a complementary strand thereof and a method for detecting prostate cancer comprising measuring the miRNA in vitro.
Claims4
A method for detecting prostate cancer and then treating or performing a diagnostic procedure in a human subject, comprising:
- measuring an expression level of has-miR-1185-1-3p in a blood, serum, or plasma sample from the subject;
- comparing the measured expression level of hsa-miR-1185-1-3p to a control expression level in a sample from a healthy subject;
- and
- detecting an increased level of hsa-miR-1185-1-3p in the sample from the subject as compared to the control expression level from the sample from the healthy subject,
- wherein the increased level of hsa-miR-1185-1-3p indicates that the subject has prostate cancer, and
- and further treating the subject for the prostate cancer or performing a diagnostic procedure on the subject with the prostate cancer;
- wherein the treating comprises surgery, radiotherapy, chemotherapy or the combination thereof;
- and
- wherein the diagnostic procedure comprises rectal examination, transrectal ultrasonography of the prostate, or imaging of prostate tissue.
Dependencies are inferred from the claim text.