Method and kit for predicting the risk of deep vein thrombosis and pulmonary embolism

A method for identifying if a woman subject undergoing a change in hormone levels is at risk of developing a blood clotting disease, the method comprising:

• determining, in a sample from said woman subject, genotyping data including the single nucleotide polymorphisms of rs1799853 (SEQ ID NO:
• 1) and rs4379368 (SEQ ID NO:
• 2), wherein the presence of allele T in rs1799853 (SEQ ID NO:
• 1) and allele T in rs4379368 (SEQ ID NO:
• 2) in heterozygous or homozygous form indicates that said woman subject has an increased risk of developing a blood clotting disease;
• and
• administering an effective amount of a compound adapted to the prevention of the blood clotting disease to the woman subject based on the risk for developing a blood clotting disease,
• wherein the blood clotting disease is selected from the group consisting of deep vein thrombosis, pulmonary embolism, vein thrombosis, and arterial thrombosis.