Microorganism strain for high-performance metabolism of biomass-derived carbon source
AssigneesPostech Academy-Industry Foundation, Seoul National University R&Db Foundation
InventorsGyoo Yeol Jung, Dong Hun Kwak, Sang Woo Seo, Hyun Gyu Lim
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Abstract
The present invention relates to a novel microorganism capable of metabolizing various carbon sources at high rates. A novel microorganism according to the present invention was observed to grow at a very high rate in a minimal medium/nutrient medium, etc., compared to microorganisms such as Escherichia coli, and shows resistance at a high initial sugar/salt concentrations as well as being able to produce lycopene and 2,3-butanediol through genetic manipulation. Therefore, the novel microorganism can be used in various production fields of high value-added compounds using microorganisms.
Claims11
A transformed Vibrio sp. DHG strain with improved metabolic efficiency for carbon sources,
- wherein the transformed Vibrio sp. DHG strain is obtained by introducing a SXT recombination system expression cassette into a Vibrio sp. DHG strain having accession number KCTC13239BP;
- wherein the Vibrio sp. DHG strain having accession number KCTC13239BP comprises a 16S rDNA gene consisting of the nucleotide sequence of SEQ ID NO:
- 1;
- wherein the SXT recombination system expression cassette comprises a synthetic 5′ UTR (untranslated region) consisting of the nucleotide sequence of SEQ ID NO:
- 57;
- a promoter consisting of the nucleotide sequence selected from the group consisting of SEQ ID NOs:
- 22 to 35 and 56;
- and a gamma gene consisting of the nucleotide sequence of SEQ ID NO:
- 6;
- and
- wherein the carbon source comprises at least one selected from the group consisting of glucose, mannitol, sucrose, arabinose, galactose, glycerol and alginic acid.
Dependencies are inferred from the claim text.