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US 11,535,826 B2Granted
Engineered 3D-printed artificial axons
AssigneeMassachusetts Institute of Technology
InventorsDaniela Espinosa-Hoyos, Anna E. Jagielska, Huifeng Du, Nicholas X. Fang, Krystyn J. Van Vliet
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Abstract
Materials and methods for cell-mimetics having mechanical properties of biological neural axons are provided. A cell-mimetic device includes an array of fibers comprised of hexanediol diacrylate (HDDA) or an HDDA derivative, and at least one derivative of polyethylene glycol (PEG) selected from the group consisting of: PEG-acrylate, PEG-diacrylate, and any multi-arm PEG-acrylate.
Claims27
A cell-mimetic device comprising:
- an array of fibers comprised of a material comprising:
- hexanediol diacrylate (HDDA);
- and
- at least one of PEG-acrylate, PEG-diacrylate, and a multi-arm PEG-acrylate, wherein at least a subset of the array of fibers is free-standing pillars.
1 more element
Dependencies are inferred from the claim text.