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US 11,535,647 B2Granted
Peptide purification method using sulfonate compound
AssigneeNagase & Co., Ltd.
InventorsKeisuke Matsuyama, Kenichiro Yamamoto, Sayoko Murakami
Life of this patent
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Abstract
A method for purifying a target peptide may include mixing a peptide product obtained through a peptide synthesis with a solvent in the presence of a sulfonic acid compound to obtain a solid; and performing a solid-liquid separation to collect the solid.
Claims24
A method for purifying a target peptide from a peptide product obtained through a peptide synthesis, wherein the target peptide is free at the N-terminus and/or comprises at least one basic amino acid residue, the method comprising:
- (1) mixing the peptide product with a solvent in the presence of a sulfonic acid compound to provide a solid;
- (2) performing a solid-liquid separation to collect the solid.
Dependencies are inferred from the claim text.