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US 11,535,642 B2Granted
Trehalose analogues
AssigneeCentral Michigan University
InventorBenjamin M. Swarts
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Abstract
Described herein are trehalose analogues. Also described herein are methods of making the trehalose analogues and uses of the analogues. For example, the disclosed trehalose analogues may be useful in the detection of bacteria.
Claims20
A compound according to formula (I):
- wherein
- Y is O or NH;
- Z is alkynyl, —N3, a label, or a therapeutic;
- and
- n is 0 to 50,
- wherein C1-n alkylene is optionally substituted.
3 more elements
A compound according to formula (II):
- wherein
- Y1 is O or NH;
- Y2is alkynyl, —N3, OC(O)Ci1-n alkylene-Z2, or NHC(O)C1-n alkylene-Z2;
- Z1 and Z2 are each independently selected from the group consisting of alkynyl, —N3, quencher, a label, and a therapeutic;
- and
- n is 0 to 50,
- wherein C1-n alkylene is optionally substituted.
4 more elements
Dependencies are inferred from the claim text.