Back to results
US 11,535,627 B2Granted
Pyrimidine derivative compound, pharmaceutically acceptable salt thereof, preparation process thereof, and pharmaceutical composition using the same
AssigneeSpark Biopharma, Inc.
InventorsSeung Bum Park, Jonghoon Kim
Life of this patent
Estimating the term…
Abstract
The present invention is related to a novel pyrimidine derivative compound or a pharmaceutically acceptable salt thereof, a process for preparing the same, and a pharmaceutical composition using the same.
Claims6
A pyrimidine derivative compound represented by Formula VIII:
- wherein
- F is —X—(CH2)n-(O—CH2)m- and forms a 3- to 6-membered heterocyclic ring together with adjacent N and C atoms wherein X is
- or —CH2—, and wherein (i) when n is 0, m is 0 or 1, (ii) when n is 1, m is 0 or 1, and (iii) when n is 2, m is 0;
- R3 is hydrogen, a —C1 to C3 alkyl group, an allyl group, -Tf, a C1 to C3 alkyl benzyl group, or
- and
- R6 is
- wherein R and R′ are each independently a benzyl group or a C1 to C3 alkyl group.
4 more elements
A compound represented by any one of the following formulas:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.