Device and method for the quantification of cellular and non-cellular blood components

A device for the quantification of cell and non-cell components in a solution containing a blood sample comprising:

• at least one pair of detection electrodes, said at least one pair of detection electrodes comprising at least one first electrode connected with a first input apt to receive a first signal in input (V+) and a second electrode;
• at least one pair of reference electrodes, said at least one pair of reference electrodes comprising a first electrode connected with a second input configured to receive a second signal in input (V+) of opposite polarity to the first input signal (V+) and a second electrode connected to the second electrode of said at least one pair of detection electrodes, in a common point wherefrom an output signal (Out) is picked up;
• said device comprising:
• at least one concentrator in ferromagnetic material and cooperating with a magnetic field external to the device to cause the concentration of said components on said at least one pair of detection electrodes;
• a substrate having a first side and a second side that is opposite of the first side;
• a support configured to receive a sample of blood or of solution containing blood;
• at least one spacer element connected to and extending between said substrate and said support so that the support is spaced apart from the substrate, said at least one spacer element is configured to confine in the plane of the substrate the blood sample and to distance said substrate from said support;
• wherein said at least one pair of detection electrodes are attached to the first side of the substrate;
• wherein said at least one pair of reference electrodes are attached to the second side of the substrate;
• wherein said at least one concentrator is carried by said substrate;
• and
• wherein said at least one spacer element confines the blood sample in the plane of the substrate so that the blood sample does not contact said substrate, said at least one pair of detection electrodes, and said at least one pair of reference electrodes.