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US 11,534,701 B2Granted
Fluid degassing control system
AssigneeIDEX Health & Science LLC
InventorsCarl Sims, Quan Liu, David Wert
Life of this patent
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Abstract
A membrane-based fluid degassing system is arranged for automated control to a degassing efficiency set point, so that fluid is degassed only as necessary. The control variable may be assigned as the degassing environment, to provide the gas transfer driving force suitable to appropriately degas the fluid. By avoiding unnecessary degassing of the fluid, mobile phase pervaporation through the membrane is minimized.
Claims11
A fluid degassing system, comprising:
- a degassing module having a chamber and a gas-permeable membrane forming a non- porous barrier separating said chamber into a retentate side and a permeate side, said degassing module including a fluid inlet port and a fluid outlet port each fluidically connected to the retentate side of said chamber, and an exhaust port fluidically connected to the permeate side of said chamber;
- a vacuum pump fluidically connected to said exhaust port for evacuating the permeate side of said chamber;
- a fluid pump fluidically connected to at least one of said fluid inlet port and said fluid outlet port for motivating a fluid through the retentate side of said chamber at an adjustable fluid flow rate;
- an input means including a user interface for inputting one or more process condition values including a degassing efficiency parameter value;
- and
- a control system communicatively linked to said input means and said vacuum pump, said control system including a pressure sensor arranged to sense a pressure of the permeate side of said chamber, a database storing calibration data defining permeate side pressure set point levels that achieve degassing efficiency parameters at respective fluid flow rates, wherein the calibration data is specific to the particular degassing module, the control system further including a processor programmed to apply a user inputted degassing efficiency parameter value and the fluid flow rate to the calibration data to dynamically determine a maximum pressure value for the permeate side of said chamber as a calculated pressure set point that nevertheless permits the degassing efficiency parameter value to be met through solution-diffusion gas transfer through the non-porous barrier, the degassing efficiency parameter being defined by at least one of a degassing efficiency and a residual gas concentration, with the degassing efficiency being defined by:
- e=100% - % residual gas
- wherein:
- e=degassing efficiency;
- and
- % residual gas = the amount by weight of gas in the fluid after degassing divided by the amount by weight of gas in the fluid at saturation, each measured at the same pressure, said control system being adapted to generate and deliver a pressure control signal to said vacuum pump to seek a permeate side pressure equal to the pressure set point.
8 more elements
Dependencies are inferred from the claim text.