Blood glucose monitoring and controlling system

A blood glucose monitoring and controlling system, comprising:

• a detecting device comprising a first microneedle patch, a liquid pumping actuator, a sensor and a monitoring and controlling chip, wherein:
• the first microneedle patch comprises a plurality of hollow microneedles configured to be attached to and punctured into skin of a human subject to draw a tissue liquid;
• the liquid pumping actuator comprises a liquid guiding channel, a first actuating unit, a first carrier body, a first compressing chamber and a liquid storage chamber, the liquid guiding channel is in fluid communication with the first microneedle patch, and the first actuating unit is constructed on the first carrier body and covers and seals the first compressing chamber, the first microneedle patch is attached on the first carrier body and is opposite to the first actuating unit, and first actuating unit is actuated to generate a first pressure difference in the liquid guiding channel to draw the tissue liquid and allow the liquid guiding channel to draw the tissue liquid transported by the hollow microneedles, wherein the liquid guiding channel comprises an inlet channel and a liquid storage channel separately disposed in the first carrier body, the first compressing chamber is in fluid communication with the inlet channel and the liquid storage channel, and the liquid storage channel is in fluid communication with the liquid storage chamber, wherein a valve membrane is disposed in the inlet channel and the liquid storage channel to control an open/closed state of the inlet channel and the liquid storage channel;
• the sensor is packaged in a system-in-package manner on the first carrier body and is disposed in the liquid storage chamber and is in communication with the liquid guiding channel to measure a blood glucose level in the tissue liquid and transmits a measured data of the blood glucose level to the monitoring and controlling chip;
• and
• the monitoring and controlling chip generates blood glucose level information by calculating the measured data and transmits a notification of the blood glucose level information;
• and
• a liquid supplying device comprising a second microneedle patch, a liquid supplying actuator, a liquid supplying chamber and a liquid supplying and controlling chip, wherein:
• the second microneedle patch comprises a plurality of hollow microneedles configured to be attached to and punctured into the skin of the human subject;
• the liquid supplying actuator comprises a liquid injection channel, a second actuating unit, a second carrier body and a second compressing chamber, the second actuating unit is constructed on the second carrier body and covers and seals the second compressing chamber, the second microneedle patch is attached on the second carrier body and is opposite to the second actuating unit, and the liquid injection channel is in fluid communication with the second microneedle patch and the liquid supplying chamber;
• the liquid supplying chamber stores an insulin liquid, and the second actuating unit is actuated to compress the liquid injection channel to conduct liquid transportation;
• and
• the liquid supplying and controlling chip receives the notification of the blood glucose level information transmitted from the monitoring and controlling chip of the detecting device so as to actuate the second actuating unit of the liquid supplying device so that a second pressure difference is generated in the liquid injection channel to transport the insulin liquid stored in the liquid supplying chamber and guide the insulin liquid to the hollow microneedles, thereby injecting the insulin liquid into subcutaneous tissue of the human subject to stabilize the blood glucose level.