Phosphorus-sparing nutritional composition
AssigneeAlbion Laboratories, Inc.
InventorJonathan David Bortz
Life of this patent
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Abstract
A nutritional composition comprises (a) one to a plurality of physiologically acceptable calcium salts and/or chelates and (b) one or more phosphorus-containing components, such as phosphate salts, and/or phosphorus-rescuing components, such as phytase. The composition is useful for phosphorus-sparing calcium supplementation of the diet of a human subject, and for treatment of a low bone density condition in a human subject in need thereof.
Claims20
A composition comprising
- (a) one to a plurality of physiologically acceptable calcium salts and/or chelates, at least about 5% of the molar amount of calcium in the composition being in the form of one or more organic acid salts and/or organic chelates of calcium, and
- (b) one or more phosphorus-containing components, wherein the total molar amount of phosphorus delivered by such phosphorus-containing component(s) is calculated to be about 33% to about 300% of the molar amount of calcium in the composition,
- wherein the composition delivers phosphorus-sparing functionality whereby a reduction in phosphorus availability associated with calcium supplementation is mitigated or eliminated.
A composition comprising
- (a) one to a plurality of calcium salts and/or chelates independently selected from the group consisting of calcium carbonate, monocalcium phosphate (MCP), dicalcium phosphate (DCP), hydroxyapatite, calcium citrate tetrahydrate, calcium citrate malate (CCM), calcium formate, calcium gluconate, calcium glycerophosphate, calcium bisglycinate, calcium lactate, calcium levulinate, dicalcium malate (DCM), calcium succinate and calcium tartrate;
- and
- (b) one or more phosphorus-containing component, wherein the total molar amount of phosphorus delivered by such phosphorus-containing component(s) is calculated to be about 33% to about 300% of the molar amount of calcium in the composition;
- wherein the composition delivers phosphorus-sparing functionality whereby a reduction in phosphorus availability associated with calcium supplementation is mitigated or eliminated.
A composition comprising
- (a) one to a plurality of physiologically acceptable calcium salts and/or chelates in a total amount equivalent to about 75 to about 750 mg elemental calcium per unit dose;
- and
- (b) at least one phytase in a total amount of about 0.1 to about 10 FTU per mg elemental calcium equivalent.
A composition comprising one to a plurality of dose units, each dose unit comprising (a) about 250 to about 800 mg in total of one or more calcium salts and/or chelates and (b) a phosphorus-containing component that is separate from or partly or wholly provided by said one or more calcium salts and/or chelates;
- wherein the molar ratio of calcium to phosphorus delivered by each dose unit is about 1:3 to about 3:1, and wherein the composition delivers phosphorus-sparing functionality whereby a reduction in phosphorus availability associated with calcium supplementation is mitigated or eliminated.
Dependencies are inferred from the claim text.