Emulsion composition for chemoembolization and method for producing same

An emulsion composition for chemoembolization, comprising

• a polymer nanoparticle comprising a water-soluble anticancer agent, a water-insoluble anticancer agent, or a combination thereof as active ingredients, and an amphiphilic block copolymer comprising a hydrophilic (A) block and a hydrophobic (B) block;
• a water-soluble contrast agent;
• and
• a water-insoluble contrast agent,
• wherein the hydrophilic (A) block is one or more selected from the group consisting of monomethoxypolyethylene glycol, monoacetoxypolyethylene glycol, polyethylene glycol, copolymer of polyethylene and propylene glycol, and polyvinyl pyrrolidone, and
• the hydrophobic (B) block is one or more selected from the group consisting of polylactide, polyglycolide, polycaprolactone, polydioxan-2-one, copolymer of polylactide and glycolide, copolymer of polylactide and polydioxan-2-one, copolymer of polylactide and polycaprolactone and copolymer of polyglycolide and polycaprolactone;
• and
• the water-soluble contrast agent is iopamidol, and the water-insoluble contrast agent is one or more selected from the group consisting of poppy fruit-derived iodized oil, soybean-derived iodized oil and ethiodol,
• wherein the diameter of the polymer nanoparticle is 10 nm to 60 nm.