Applications of novel thiazole derivative in treating inflammatory bowel diseases
AssigneeEast China University of Science and Technology
InventorsHonglin Li, Zhenjiang Zhao, Rui Wang, Yufang Xu, Wanqi Wang, Yingfang Yang
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Abstract
The present invention relates to applications of a novel thiazole derivative in treating ulcerative colitis and in the preparation of drugs for treating ulcerative colitis. The present invention specifically relates to applications of a compound represented by formula I and a pharmaceutical composition containing the compound represented by formula I, in treating ulcerative colitis and in the preparation of drugs for treating ulcerative colitis:
Claims4
A method for treating inflammatory bowel disease, comprising administrating a compound of formula II or a pharmaceutically acceptable salt or ester thereof or a pharmaceutical composition to a subject in need of the treatment of inflammatory bowel disease, wherein the pharmaceutical composition comprises a compound of formula II or a pharmaceutically acceptable salt or ester thereof and a pharmaceutically acceptable carrier or excipient;
- and the compound of formula II is represented by:
- Wherein,
- R1 is a substituted or unsubstituted C1-C3 alkyl;
- R5 and R6 are independently selected from the group consisting of H, halogen and a substituted or unsubstituted C1-C3 alkyl;
- R3 is selected from the group consisting of H and a substituted or unsubstituted C1-C3 alkyl;
- and
- R7, R8 and R9 are independently selected from the group consisting of H and halogen.
A method for treating inflammatory bowel disease, comprising administrating a compound or a pharmaceutically acceptable salt or ester thereof or a pharmaceutical composition to a subject in need of the treatment of inflammatory bowel disease, wherein the pharmaceutical composition comprises a compound or a pharmaceutically acceptable salt or ester thereof and a pharmaceutically acceptable carrier or excipient;
- and the compound is selected from the group consisting of:
Dependencies are inferred from the claim text.