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US 11,534,388 B2Granted
Compositions and kits for the removal of irritating compounds from bodily surfaces
AssigneeAveritas Pharma Inc.
InventorsArturo J. Angel, Larry W. Litle, Keith R. Bley, Allan L. Wilcox, Gene C. Jamieson, Naweed Muhammad
Life of this patent
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Abstract
The invention provides compositions, methods and kits for the removal of harmful or irritating substances from bodily surfaces. Kits may include a composition containing capsaicin and a capsaicin-cleansing composition, e.g., a composition in which capsaicin is soluble.
Claims16
A method for treating neuropathic pain associated with postherpetic neuralgia comprising:
- a) applying to a bodily surface affected by neuropathic pain associated with postherpetic neuralgia a first composition comprising capsaicin or a capsaicin analog in a total concentration from 5% to 10% by weight of the first composition;
- and
- b) cleansing the bodily surface after the step a) by
- i) applying to the bodily surface a second composition for at least a time period sufficient to solubilize at least 10% w/w of the capsaicin or the capsaicin analog, wherein the second composition comprising about 80 to about 99 percent w/w polyethylene glycol (PEG) is a surfactant-free gel;
- and
- ii) removing the second composition after the step i) from the bodily surface.
3 more elements
A method for treating neuropathic pain associated with diabetic neuropathy comprising:
- a) applying to a bodily surface affected by neuropathic pain associated with diabetic neuropathy a first composition comprising capsaicin or a capsaicin analog in a total concentration from 5% to 10% by weight of the first composition;
- and
- b) cleansing the bodily surface after the step a) by
- i) applying to the bodily surface a second composition for at least a time period sufficient to solubilize at least 10% w/w of the capsaicin or the capsaicin analog, wherein the second composition comprising about 80 to about 99 percent w/w polyethylene glycol (PEG) is a surfactant-free gel;
- and
- ii) removing the second composition after the step i) from the bodily surface.
3 more elements
A topical system for treating neuropathic pain associated with diabetic neuropathy comprising:
- a) a first composition for applying to a bodily surface affected by neuropathic pain associated with diabetic neuropathy, comprising capsaicin or a capsaicin analog in a total concentration from 5% to 10% by weight of the first composition;
- and
- b) a second composition for cleansing the capsaicin from the bodily surface after applying the first composition, comprising:
- i) about 80 to about 99 percent w/w polyethylene glycol (PEG);
- and
- ii) about 0.1 to about 4.0 percent w/w polyacrylate thickening agent,
- wherein the second composition has a viscosity of between 100 to 8000 cps.
4 more elements
Dependencies are inferred from the claim text.