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US 11,534,382 B2Granted
Topical compositions and methods of using the same
AssigneeNovan, Inc.
InventorsNathan Stasko, Ryan Doxey
Life of this patent
Estimating the term…
Abstract
The present invention relates generally to compositions and methods of using the same such as, for example, methods of treating the skin of a subject using a composition as described herein. The composition may comprise a diluent, a solvent, a penetration enhancing agent, a skin brightening agent, a skin renewing agent, a thickening agent, an anti-irritant, a chelating agent, an active pharmaceutical ingredient (API), optionally a pH adjustment agent, and optionally a preservative. The composition may further comprise L-arginine and/or L-citrulline and/or esters and/or derivatives thereof.
Claims19
A topical composition comprising:
- a diluent, wherein the diluent is water and water is present in an amount of about 60% to about 95% by weight of the topical composition:
- a solvent, wherein the solvent comprises an alcohol:
- a penetration enhancing agent, wherein the penetration enhancing agent comprises a glycol ether;
- a skin brightening agent, wherein the skin brightening agent comprises a peptide comprising the amino acid sequence of SEQ ID NO:1:
- a skin renewal agent, wherein the skin renewal agent comprises a peptide;
- a thickening agent, wherein the thickening agent comprises a polyacrylate polymer;
- an anti-irritant;
- a chelating agent;
- an active pharmaceutical ingredient (API) selected from the group consisting of salicylic acid, a nitric oxide (NO)-releasing compound, and any combination thereof;
- optionally a pH adjustment agent;
- and
- optionally a preservative.
9 more elements
Dependencies are inferred from the claim text.