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US 11,530,979 B2Granted
Multifocal photoacoustic microscopy through an ergodic relay
AssigneeCalifornia Institute of Technology
InventorsLihong Wang, Yang Li, Tsz Wai Wong
Life of this patent
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Abstract
Multifocal photoacoustic imaging systems and methods that implement an ergodic relay to encode photoacoustic signals detected from a plurality of illuminated optical foci regions.
Claims36
A multifocal photoacoustic imaging system comprising:
- a pattern-generating device configured to generate a plurality of illumination beams, the plurality of illumination beams having focal spots located in corresponding optical foci regions of a field-of-view of a sample being imaged;
- an ergodic relay in optical communication with the pattern-generating device and acoustically coupled to the sample, the ergodic relay configured to encode photoacoustic signals received from the illuminated optical foci regions;
- and
- an ultrasonic transducer device in acoustic communication with the ergodic relay.
1 more element
A multifocal photoacoustic imaging method, comprising:
- (a) controlling a pattern-generating device to generate a plurality of illumination beams with focal spots illuminating a corresponding plurality of optical foci regions in a field-of-view of a sample being imaged;
- (b) receiving encoded photoacoustic signals detected by an ultrasound transducer device in acoustic communication with an ergodic relay, wherein the ergodic relay is in acoustic communication with the sample being imaged;
- and
- (c) reconstructing a snapshot photoacoustic image using calibrated system responses and the encoded photoacoustic signals.
1 more element
Dependencies are inferred from the claim text.