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US 11,530,437 B2Granted
Magnetic particles
AssigneeBeckman Coulter, Isse.
InventorsJeffrey J. Corpstein, Evan Farthing, Thomas G. Keen, Jianli Zhao, Asmita Patel, Yuandan Liu, Cuong N. Hoang, Emmet Welch
Life of this patent
Estimating the term…
Abstract
A magnetic particle is disclosed. The magnetic particle comprises a magnetic material having a maximum field strength in a range of from about 20 emu/g to about 250 emu/g and a remanence in a range of from about 0 emu/g to about 30 emu/g. The magnetic particle further comprises an outer surface containing a ligand. The ligand interacts with an analyte of interest in the sample solution.
Claims24
A composition of matter for selectively binding and isolating an analyte of interest in a sample, the composition of matter comprising:
- a population of non-aggregated magnetic particles, each magnetic particle having a ferrimagnetic core;
- and a polymeric coating surrounding the ferrimagnetic core, the coating including a ligand on the surface of the coating, wherein the ligand is chemically configured to selectively bind to the analyte of interest in the sample, the population of magnetic particles having an average diameter of greater than 100 nm, a maximum field strength in a range of from about 20 emu/g to about 70 emu/g, and a remanence in a range of from about 0 emu/g to about 30 emu/g.
Dependencies are inferred from the claim text.