Gene expression cassette and expression vector including the same
AssigneeCell Biotech Co., Ltd.
InventorMyung Jun Chung
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Abstract
The present invention relates to a gene expression cassette including a strong promoter derived from lactic acid bacteria, and a gene expression vector including the same. According to the present invention, a large amount of a human protein, the physiological activity of which has been verified, may be stably produced with high efficiency by introducing a useful foreign gene into an expression vector and transforming probiotics with the expression vector. Through the production of this protein, it is possible to provide a basis for developing functional probiotics and making products using them.
Claims13
A gene expression cassette comprising:
- at least one promoter operably linked to a heterologous nucleic acid encoding a biologically active polypeptide selected from the group consisting of SEQ ID NO:
- 1 to SEQ ID NO:
- 8;
- a nucleic acid sequence encoding a secretion signal peptide;
- and
- a selective marker gene.
Dependencies are inferred from the claim text.