Bioenvironmental simulation device and method
AssigneesSeoul National University R&Db Foundation, Seoul National University Hospital
InventorsSeung Hee Yang, Yon Su Kim, Dong Ki Kim, Sa Ram Lee, Yong Chul Kim, Mi Yeon Yu, Ji Eun Kim
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Abstract
The bioenvironmental simulation device according to an embodiment of the present invention includes at least one mounting unit on which cells to be measured are placed, a rotational force application unit configured to rotate the mounting unit so as to apply a rotational force to the cells to be measured placed on the mounting unit, and a culture liquid flow device through which a culture liquid flows across the mounting unit, wherein the culture liquid flows by the culture liquid flow device so as to apply a shear force to the cells to be measured.
Claims17
A bioenvironmental simulation device, comprising:
- a mounting unit on which cells to be measured are placed;
- a motor configured to rotate the mounting unit so as to apply a rotational force to the cells to be measured placed on the mounting unit;
- and
- a culture liquid flow device through which a culture liquid flows across the mounting unit, wherein the culture liquid flows by the culture liquid flow device so as to apply a shear force to the cells to be measured,
- wherein the mounting unit comprises:
- a unit body forming an inner space;
- a separation membrane disposed in the unit body and partitioning the inner space into a first space and a second space disposed under the first space;
- a first mounting part including the first space through which a first culture liquid passes;
- and
- a second mounting part including the second space through which a second culture liquid passes,
- wherein the cells are placed on one surface and an opposing surface of the separation membrane,
- wherein the rotational force and the shear force are applied to the one surface and the opposing surface of the separation membrane.
Dependencies are inferred from the claim text.