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US 11,530,219 B2Granted
Ligands to cereblon (CRBN)
AssigneeDana-Farber Cancer Institute, Inc.
InventorsNathanael Gray, Tinghu Zhang, Eric Fischer, Zhixiang He, Guangyan Du, Katherine Donovan, Radoslaw Nowak, Jing Ting Christine Yuan
Life of this patent
Estimating the term…
Abstract
Disclosed are compounds with immunomodulatory activity, methods of making the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat diseases or disorders characterized or mediated by dysfunctional protein activity.
Claims15
A compound which is represented by any one of structures:
- or a pharmaceutically acceptable salt or stereoisomer thereof.
Dependencies are inferred from the claim text.