Multiple blood bag system

A method for high throughput preparation of blood products to be used for blood transfusion, the method comprising the following steps:

• providing a closed disposable sterile multiple blood bag system comprising:
• a fluid collecting bag (B.00) comprising at least one outlet port, said fluid collecting bag containing whole blood obtained from an individual;
• first and second sampling bags (B.10, B.12), each comprising at least one inlet port and at least one outlet port;
• a second buffer bag (B.11) comprising at least one outlet port;
• said second buffer bag (B.11) containing a buffer medium;
• third and fourth sampling bags (B.20, B.22), each comprising at least one inlet port and at least one outlet port;
• first means for transferring fluid (AS0) from the first collecting bag (B.00) to the sampling bags (B.10, B.12), and second means for transferring fluid (AS1) from the first sampling bag (B.10) to the third and fourth sampling bags (B.20, B.22), wherein the first and second means for transferring fluid (AS0, AS1) each comprise:
• a channel extending along a longitudinal axis, the channel having a cross section with a width measured along a first transverse axis and a thickness measured along a second transverse axis (z) perpendicular to the first transverse axis, the width being greater than or equal to the thickness, the channel having first and second walls along the second transverse axis (z);
• at least one inlet in fluid communication with the channel;
• at least first and second outlets in fluid communication with the channel, the first outlet being separated, on the second transverse axis (z), from the second outlet;
• and
• the at least one outlet port of the fluid collecting bag (B.00) is sterilely and fluidly connected to the at least one inlet of the first means for transferring fluid (AS0) and the at least first and second outlets of the first means for transferring fluid (AS0) are sterilely and fluidly connected to the at least one inlet port of respectively the first and second sampling bags (B.12, B.10);
• the at least one outlet port of the first sampling bag (B.10) is fluidly and sterilely connected to the at least one inlet of the second means for transferring fluid (AS1), the at least first and second outlets of the second means for transferring fluid (AS1) are fluidly and sterilely connected to the inlet port of respectively the third and fourth sampling bags (B.20, B.22), and the at least one outlet port of the second buffer bag (B.11) is fluidly and sterilely connected to the at least one inlet of the second means for transferring fluid (AS1);
• and
• applying acoustic field inside the channel of the means for transferring fluid (AS0) by means of an acoustic wave generator;
• transferring the content of the fluid collecting bag (B.00) in the first means for transferring fluid (AS0);
• and
• collecting blood cells in the first sampling bag (B.10) and blood plasma in the second sampling bag (B.12);
• applying acoustic field inside the channel of the second means for transferring fluid (AS1) by means of the acoustic wave generator;
• transferring the content of the first sampling bag (B.10) and the second buffer bag (B.11) in the second means for transferring fluid (AS1);
• and
• collecting red blood cell concentrate in the third sampling bag (B.20) and platelet concentrate in the fourth collecting bag (B.22).