Non-fibrous porous film and method for tissue adhesion

A non-fibrous porous film, which is manufactured by a method for manufacturing a non-fibrous porous film, wherein the method for manufacturing a non-fibrous porous film comprises:

• preparing a polymer mixture solution, wherein the polymer mixture solution comprises:
• polycaprolactone (PCL);
• and
• at least one hydrophobic polymer, which is selected from a group consisting of polylactic acid (PLA), poly(lactic-co-glycolic acid (PLGA), poly(glycolic acid) (PGA), polyhydroxybutyrate (PHB), polydioxanone (PDS), poly(propylene fumarate) (PPF), polyanhydrides, polyacetals, poly(ortho esters), polycarbonates, polyurethanes, polyphosphazenes and polyphosphoester, wherein the molecular weight of the at least one hydrophobic polymer is 10K-800K;
• adding solid particles as a dispersing agent to the polymer mixture solution and mixing the solid particles with the polymer mixture solution, wherein the amount of solid particles added is enough to convert the polymer mixture solution into a solid mixture, wherein the particle size of the solid particles is 50-250 μm;
• drying the solid mixture to form a film;
• and
• washing the film with a washing fluid to remove the solid particles from the film to form a porous film,
• wherein the weight ratio of the polycaprolactone to the at least one hydrophobic polymer is 1:0.1 to 1:10, and wherein the weight ratio of the polycaprolactone and the at least one hydrophobic polymer to solid particles is 1:0.01 to 1:250, and
• wherein the real density of the non-fibrous porous film is 1.5-5.0×10−3 g/cm2.