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US 11,529,389 B2Granted
Delivering biological drugs to tissues
AssigneeUniversity of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsRobert Michael Queen Shanks, Jes K. Klarlund
Life of this patent
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Abstract
Disclosed herein are fusion proteins for use in treating an inflammatory or immune disorder and methods of use. In some examples, the fusion proteins include an anchor domain and a therapeutic polypeptide. In some examples, the fusion proteins and methods herein can be used to treat inflammatory or immune disorders.
Claims14
A fusion protein comprising an anchor domain and a therapeutic polypeptide, wherein
- the anchor domain comprises a wheat germ agglutinin (WGA) anchor domain, and
- the therapeutic polypeptide comprises
- an antibody that specifically binds to, and is an antagonist of, interleukin (IL)-17A.
Dependencies are inferred from the claim text.