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US 11,529,346 B2Granted
Vaginal gel
AssigneeNational Medical Supply, LLC
InventorsRobert J. Borgman, James E. Juul
Life of this patent
Estimating the term…
Abstract
A composition having gel-like consistency contains metronidazole, terconazole, a physiologically acceptable thickener and water. The composition is useful for treating bacterial vaginosis as well as vulvovaginal candidiasis.
Claims5
A composition having enhanced bioavailability of metronidazole, a gel-like consistency and comprising metronidazole, terconazole, a physiologically acceptable thickener, and water;
- wherein metronidazole is present in a concentration of at least 0.5 weight percent based on the weight of the composition, terconazole is present in a concentration of at least 0.4 weight percent, based on the weight of the composition, and in an amount sufficient to enhance bioavailability of metronidazole present and the metronidazole is present together with a buffer system which provides a buffered pH value for the composition in the range of 3.75 to 4.25, and metronidazole and terconazole are present in a mole ratio in the range of 3:1 to about 3.5:1.
Dependencies are inferred from the claim text.