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US 11,529,321 B2Granted
Use of aminomethylenecyclohexane-1,3-dione compound
AssigneeWigen Biomedicine Technology (Shanghai) Co., Ltd.
InventorsCheng Luo, Liyan Yue, Wei Wan, Yuanyuan Zhang, Hualiang Jiang, Kaixian Chen
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Abstract
The present invention relates to use of an aminomethylenecyclohexane-1,3-dione compound, more particularly to use of a compound shown in the following formula (I) or a pharmaceutically acceptable salt thereof alone or in combination with other drug in preparing a drug for regulating or treating a disease related to autophagy, especially mammalian ATG8 homologous proteins.
Claims2
A method for inhibiting LC3 proteins in a human body comprising:
- treating the human body with a compound or a pharmaceutically acceptable salt thereof, alone or in combination with other drugs, to inhibit the LC3 proteins,
- wherein the LC3 proteins are selected from the group consisting of LC3A, LC3B and LC3C proteins, and
- wherein the compound is selected from the group consisting of the following compounds:
- Compound
- Structure
- 1
- 2
- 3
- 4
- 5
- 6
- 7
9 more elements
Dependencies are inferred from the claim text.