Devices and methods for delivery of substances to animals
AssigneeRuminant Biotech Corp Limited
InventorsMark Christopher Lay, Hayden Peter Thomas, Neil Richard Gladden, David Leslie Hayman, Geoffrey Earle Corbett, Prabhat Bhusal
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Abstract
The invention provides a delayed release dosage form and a bolus configured for administration to an animal, wherein the dosage form and the bolus is configured to release a hydrophobic substance to the animal over a period of time. Preferably the hydrophobic substance is a haloform. Also provided is the use of the delayed release dosage form or bolus of the invention to reduce methane production in a ruminant animal. Also provided is the method of manufacturing a bolus of the invention.
Claims28
A delayed release dosage form or a bolus configured for administration to a ruminant animal, wherein said dosage form and said bolus is configured to release an effective amount of a methane inhibiting agent to the animal over a period of time, wherein said delayed release dosage form or said bolus comprises:
- a core, wherein the core comprises the methane inhibiting agent to be administrated to the ruminant animal mixed with a carrier;
- and
- a housing which covers at least a portion of the core;
- wherein, the bolus is configured to release the methane inhibiting agent through the housing over a predetermined period of time;
- and
- wherein the methane inhibiting agent is a haloform selected from the group consisting of bromoform, chloroform, iodoform, and combinations thereof;
- and
- wherein the haloform is present in the core and the carrier comprises a wax.
A method of manufacture of a bolus configured for administration to an animal, wherein said bolus is configured to release an effective amount of a methane inhibiting agent to the animal over a period of time , comprising:
- a. forming a housing which has a cavity;
- b. forming a core which includes the methane inhibiting agent to be administrated to the ruminant animal mixed with a carrier;
- c. transferring the core to the cavity, and wherein the methane inhibiting agent is a haloform selected from the group consisting of bromoform, chloroform, iodoform, and combinations thereof;
- and wherein the carrier comprises a wax.
Dependencies are inferred from the claim text.