Composition for treatment of overactive bladder

An acidic nutritional supplement composition effective for the treatment of overactive bladder (OAB), comprising therapeutically effective amounts of pumpkin seed extract,

• nitric oxide precursor,
• vitamin D3,
• prebiotic fiber,
• a preservative, and
• a stabilizer;
• wherein the preservative is at least one selected from the group consisting of potassium sorbate, malic acid, tartaric acid, citric acid, sorbic acid, succinic acid, benzoic acid, lactic acid, propionic acid, sodium sulfite, sodium bisulfite, sodium metabisulfite, potassium bisulfite, potassium metabisulfite, vitamin E (tocopherol), vitamin C (ascorbic acid), butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), disodium ethylenediaminetetraacetic acid (EDTA), and polyphosphates:
• wherein the preservative is sufficient to decrease the pH of the nutritional supplement composition to 4.0-4.5 to inhibit bacteria growth;
• and
• wherein the stabilizer is
• cellulose gum, and
• optionally, at least one selected from the group consisting of polyglycerol polyricinoleate (PGPR), ammonium phosphatide (AMP), mono and diglycerides, carob (locust bean gum), agar-agar carrageenan, pectin, calcium chloride, lecithin, alginates (from seaweed), alginic acid, gelatin, guar gum, gum arabic (acacia), ghatti gum, potassium alginate, karaya gum, tragacanth gum, and xanthan gum;
• wherein the following amounts are contained in a daily administered unit dose:
• pumpkin seed extract 100 mg-1,000 mg,
• nitric oxide precursor 50 mg-10,000 mg,
• vitamin D3 300 IU-10,000 IU, and
• prebiotic fiber 500 mg-15,000 mg.