Chimeric M. hyorhinis polyprotein for vaccines and diagnostics
AssigneeIowa State University Research Foundation, Inc.
InventorsLuis Gabriel Gimenez-Lirola, Bailey Arruda
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Abstract
The present invention is directed to novel polynucleotides, polypeptides, and polyproteins of Mycoplasma surface proteins, all of which are useful in detecting infection and for the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against Mycoplasma infections. Detection and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention. Assays, kits, systems, and nanoparticle encapsulated compositions related to the polynucleotides, polypeptides, polyproteins, antibodies or fragments, derivatives, and variants thereof are also disclosed.
Claims9
A polynucleotide encoding a chimeric polypeptide comprising Mycoplasma variable surface lipoproteins (Vlp) VlpA, VlpB, VlpC, VlpD, VlpE, VlpF, and VlpG, wherein the chimeric polypeptide comprises an amino acid sequence having at least 90% sequence identity to the sequence of SEQ ID NO:
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Dependencies are inferred from the claim text.