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US 11,524,976 B2Granted
Oligonucleotide synthesizer
AssigneeC S Bio Co.
InventorsDario Slavazza, Heng Wei Chang, Yoheng Hanson Chang
Life of this patent
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Abstract
A process for making an oligonucleotide, the process including reacting a oligonucleotide precursor with a solid phase support within a reaction vessel, the reaction vessel being coupled to an actuator and having a resting position and inverting the reaction vessel via the actuator such that the reaction vessel is inverted relative to the resting position, wherein the inversion of the reaction vessel results in stirring of the solid phase support within the reaction vessel.
Claims16
A process for making an oligonucleotide, comprising:
- reacting a oligonucleotide precursor with a solid phase support within a reaction vessel, the reaction vessel being coupled to an actuator and having a resting position;
- and
- inverting the reaction vessel via the actuator such that the reaction vessel is inverted relative to the resting position, wherein the inversion of the reaction vessel results in stirring of the solid phase support within the reaction vessel,
- wherein the reaction vessel includes a first chamber in fluid communication with a second chamber via a connecting passage, wherein the connecting passage has a width less than a width of the first chamber and the second chamber.
1 more element
Dependencies are inferred from the claim text.