Substituted aromatic compounds and related method for the treatment of fibrosis

A kit for preventing and/or slowing progression of and/or treating fibrotic disease in a subject in need thereof, wherein said kit comprises (a) a pharmaceutically acceptable salt of a compound of the formula:

• wherein
• A is straight C5 alkyl, straight C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4;
• R1 is H, F or OH;
• R2 is straight C5 alkyl, straight C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4;
• R3 is H, F, OH or CH2Ph;
• R4 is H, F or OH;
• Q is
• 1) (CH2)mC(O)OH wherein m is 1 or 2,
• 2) CH(CH3)C(O)OH,
• 3) C(CH3)2C(O)OH,
• 4) CH(F)—C(O)OH,
• 5) CF2—C(O)OH, or
• 6) C(O)—C(O)OH;
• and wherein the pharmaceutically acceptable salt of said compound is sodium, potassium, lithium, ammonium, calcium, magnesium, manganese, zinc, iron, or copper;
• and
• (b) instructions for administering a therapeutically effective amount of the pharmaceutically acceptable salt to the subject suffering from said fibrotic disease.