Method for producing alpha-allylated cycloalkanone
AssigneeKao Corporation
InventorsJun Deguchi, Makoto Sakakibara, Daichi Sakoda
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AssigneeKao Corporation
InventorsJun Deguchi, Makoto Sakakibara, Daichi Sakoda
Estimating the term…
Provided is a method with which an α-allylated cycloalkanone is obtained from a cyclic compound cycloalkanone used as a starting material. The method is a method for producing an α-allylated cycloalkanone represented by General Formula (III), and the method includes: a step 1: reacting a compound represented by General Formula (I) and alcohol having 1 or more and 4 or less of carbon atoms in the presence of a first acid catalyst and optionally a dehydrating agent; and a step 2: reacting a crude product obtained in the step 1 and a compound represented by General Formula (II) in the presence of a second acid catalyst to produce an α-allylated cycloalkanone represented by General Formula (III). The step 1 and the step 2 are consecutively performed. In the formulae above, the group -A1- (it should be noted that the front bond refers to a bond that binds to the carbon atom C1 and the back bond refers to a bond that binds to the carbon atom C2) is an alkylene group having 4 or more and 20 or less of carbon atoms that optionally contains a hetero atom and optionally has a substituent, and R4 is a hydrogen atom or an alkyl group having 1 or more and 4 or less of carbon atoms.
A method for producing an α-allylated cycloalkanone represented by Formula (III-1), comprising:
A method for synthesizing muscenone, the method comprising:
Dependencies are inferred from the claim text.