Methods of treating inflammatory skin disorders
AssigneeNepsone Ehf
InventorBirkir Sveinsson
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Abstract
A method for treating, remedying, or preventing inflammatory skin disorders by administering a therapeutically effective dose of at least one an antagonist of a calcitonin gene-related peptide receptor in a pharmaceutically acceptable formulation. The method for treating, remedying, or preventing an inflammatory skin disorder by administering topically and to the pre-psoriatic rim a therapeutically effective dose of at least one an antagonist of a calcitonin gene-related peptide receptor in a pharmaceutically acceptable formulation.
Claims2
A method of treating psoriasis in an individual in need thereof, the method comprising topically administering to a pre-psoriatic rim of the individual a pharmaceutical composition comprising a therapeutically effective dose of a calcitonin gene-related peptide (CGRP) antagonist, wherein the CGRP antagonist is heparin, and wherein the pre-psoriatic rim is a normal looking skin that is substantially adjacent to a psoriatic lesion and characterized by at least one of the following as compared to normal skin:
- increased CGRP activity, increased blood flow, fewer Langerhans cells, increased dilation of blood vessels, and increased T-cell infiltration.
Dependencies are inferred from the claim text.