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US 11,517,602 B2Granted
Traditional Chinese medicine composition for improving bone health and preparation and uses thereof
AssigneeChenland Nutritionals Inc.
InventorsShengcan Zou, Zengliang Zhang, Jiancheng Zong, Wenyu Li, Xin Li, Li Li, Shanglong Wang, Lei Zong
Life of this patent
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Abstract
A traditional Chinese medicine composition includes 60%-80% by weight of Eucommia ulmoides extract, 15%-30% by weight of Rhizoma Drynariae extract and 5%-10% by weight of Semen Cuscutae extract. A method of preparing the traditional Chinese medicine composition is also provided. Uses of the traditional Chinese medicine composition in the prevention and/or treatment of osteoporosis are also provided.
Claims5
A method of preparing a traditional Chinese medicine composition for improving bone health, comprising:
- subjecting Eucommia ulmoides, Rhizoma Drynariae and Semen Cuscutae to extraction, concentration and drying to produce Eucommia ulmoides extract, Rhizoma Drynariae extract and Semen Cuscutae extract, respectively;
- and
- mixing the Eucommia ulmoides extract, the Rhizoma Drynariae extract and the Semen Cuscutae extract uniformly to produce the traditional Chinese medicine composition;
- wherein the method specifically comprises:
- (1) subjecting Eucommia ulmoides, Rhizoma Drynariae and Semen Cuscutae to extraction respectively with an ethanol solution under refluxing and filtration;
- subjecting a residue to extraction with a solvent and filtration;
- and combining filtrates to obtain a crude Eucommia ulmoides extract, a crude Rhizoma Drynariae extract and a crude Semen Cuscutae extract, respectively;
- (2) subjecting the crude Eucommia ulmoides extract, the crude Rhizoma Drynariae extract and the crude Semen Cuscutae extract to concentration;
- introducing maltodextrin to the concentrated Eucommia ulmoides extract and the concentrated Rhizoma Drynariae extract, respectively;
- wherein the maltodextrin introduced to the concentrated Eucommia ulmoides extract is 5% by weight of Eucommia ulmoides extract;
- the maltodextrin introduced to the concentrated Rhizoma Drynariae extract is 10% by weight of Rhizoma Drynariae extract;
- spray drying or vacuum drying and sieving to produce the Eucommia ulmoides extract, the Rhizoma Drynariae extract and the Semen Cuscutae extract;
- and
- (3) mixing the Eucommia ulmoides extract, the Rhizoma Drynariae extract and the Semen Cuscutae extract uniformly in a weight ratio of (60-80):(15-30):(5-10) to produce the traditional Chinese medicine composition.
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