Back to results
US 11,510,872 B2Granted
Nanoparticle-lipid composite carriers and uses thereof
AssigneeNorthwestern University
InventorsVinayak P. Dravid, Vikas Nandwana
Life of this patent
Estimating the term…
Abstract
Provided herein are nanoparticle-lipid composite carriers as theranostic agents, particularly for diagnosis and/or treatment of cancers and related diseases and conditions. In particular embodiments, the carrier composites comprise a lipid core and an outer shell of functionalized nanoparticles (fNPs).
Claims18
A nanoparticle-lipid composite carrier, consisting of:
- (a) a hydrophobic core consisting of tails of a plurality of lipid molecules, and optionally, an active agent encapsulated in the hydrophobic core, wherein the plurality of lipid molecules is in the form of a monolayer of lipid molecules such that the nanoparticle-lipid composite carrier does not comprise a bilayer of lipid molecules;
- and
- (b) a shell consisting of surface-functionalized nanostructures assembled on heads of the plurality of lipid molecules, wherein the nanostructures are magnetic nanostructures.
Dependencies are inferred from the claim text.