Method of making a cross metathesis product
AssigneeThe Trustees of Boston College
InventorsAmir H. Hoveyda, Chaofan Xu, Xiao Shen
Life of this patent
Estimating the term…
Abstract
Method of making a cross metathesis product, the method comprising at least step (X) or step (Y): (X) reacting in a cross metathesis reaction a first compound comprising a terminal olefinic group with a second compound comprising a terminal olefinic group, wherein the first and the second compound may be identical or may be different from one another; or (Y) reacting in a ring-closing metathesis reaction two terminal olefinic groups which are comprised in a third compound; wherein the reacting in step (X) or step (Y) is performed in the presence of a ruthenium carbene complex comprising a [Ru═C]-moiety and an internal olefin.
Claims33
A method of making a cross metathesis product, the method comprising at least step (X) or step (Y):
- (X) reacting in a cross metathesis reaction a first compound comprising a terminal olefinic group with a second compound comprising a terminal olefinic group, wherein the first and the second compound may be identical or may be different from one another;
- or
- (Y) reacting in a ring-closing metathesis reaction two terminal olefinic groups which are comprised in a third compound;
- wherein the reacting in step (X) or step (Y) is performed in the presence of a ruthenium carbene complex comprising a [Ru═C]-moiety and an internal olefin which may be a Z-olefin or an E-olefin.
A method of reducing activity loss of a Ru carbene complex comprising a [Ru═C]-moiety when using said complex in a metathesis reaction in which ethylene is developed, the method comprising step (V):
- (V) performing said reaction in the presence of an internal olefin.
Dependencies are inferred from the claim text.