Use of microbial communities for human and animal health
AssigneesUniversiteit Gent, Microbial Resource Management Health NV (MRM Health)
InventorsSam Possemiers, Massimo Marzorati, Tom Van de Wiele, Ilse Scheirlinck, Pieter Van den Abeele, Selin Bolca, Davide Gottardi
Life of this patent
Estimating the term…
Abstract
The disclosure relates to a mixture of bacteria belonging to at least six or seven different and specific bacterial species preferably for use in preventing or treating gastro-intestinal disorders. Preferably, the mixture of bacteria is grown together in a fermenter prior to administering the mixture to a subject in order to prevent or treat the disorder.
Claims29
A pharmaceutical composition, wherein the composition is formulated for intestinal delivery and comprises:
- a mixture of bacterial species that are purified and present in an effective amount for increasing butyrate when measured by gas chromatography after 48 hours of in vitro growth in a culture compared to measurement of butyrate generated by an equivalent amount of any one strain of the bacterial species alone, wherein the bacterial species comprise:
- Lactobacillus plantarum;
- Anaerostipes caccae;
- and
- Faecalibacterium prausnitzii.
A pharmaceutical composition formulated for intestinal delivery, wherein the composition is in the form of a suspension and comprises:
- a mixture of bacterial species that are purified, present in an effective amount for increasing butyrate when measured by gas chromatography after 48 hours of in vitro growth in a culture compared to measurement of butyrate generated by an equivalent amount of any one strain of the bacterial species alone, wherein the bacterial species comprise:
- Lactobacillus plantarum;
- Anaerostipes caccae;
- and
- Faecalibacterium prausnitzii.
A pharmaceutical composition formulated for intestinal delivery, wherein the composition is in the form of a powder and comprises:
- a mixture of bacterial species that are purified and present in an effective amount for increasing butyrate when measured by gas chromatography after 48 hours of in vitro growth in a culture compared to measurement of butyrate generated by an equivalent amount of any one strain of the bacterial species alone, wherein bacterial species comprise:
- Lactobacillus plantarum;
- Anaerostipes caccae;
- and
- Faecalibacterium prausnitzii.
Dependencies are inferred from the claim text.