Back to results
US 11,484,567 B2Granted
Use of immune suppressive domains as medicaments
AssigneesAarhus Universitet, ISD Immunotech ApS
InventorsShervin Bahrami, Mogens Ryttergård Duch, Christian Kanstrup Holm, Magdalena Janina Laska
Life of this patent
Estimating the term…
Abstract
The present invention concerns uses of immune suppressive domains. In particular, the present invention concerns a use of an immune suppressive domain (ISD) for immune suppression and for reduction of inflammation.
Claims22
A method for relieving, alleviating, ameliorating, and/or reducing the susceptibility of an autoimmune disease, the method comprising the step of administering to a subject in need thereof a pharmaceutical composition comprising an immune suppressive domain from a virus fusion protein as an active substance,
- wherein said immune suppressive domain is from a virus of the Orthomyxoviridae family, and
- wherein said autoimmune disease is selected from the group consisting of acute disseminated encephalomyelitis (ADEM), Addison's disease, amyotrophic lateral sclerosis, ankylosing spondylodiscitis, antiphospholipid syndrome, autoimmune uveitis, celiac disease, chronic obstructive pulmonary disease, Churg-Strauss syndrome, Crohn's disease, Cushing's Syndrome, diabetes mellitus type 1, drug-induced lupus, discoid lupus erythematosus, glomerulonephritis, Goodpasture's syndrome, Graves' disease, Guillain-Barré syndrome (GBS), Hashimoto's encephalopathy, Hashimoto's thyroiditis, Henoch-Schonlein purpura, idiopathic thrombocytopenic purpura, IgA nephropathy, juvenile idiopathic arthritis, Kawasaki's disease, linear IgA disease (LAD), lupoid hepatitis, lupus erythematosus, Miller-Fisher syndrome, mixed connective tissue disease, multiple sclerosis, Myasthenia gravis, myositis, narcolepsy, neuromyelitis optica, neuromyotonia, paroxysmal nocturnal hemoglobinuria (PNH), pemphigus vulgaris, pernicious anaemia, polyarteritis nodosa, polymyalgia rheumatica, polymyositis, primary biliary cirrhosis, primary sclerosing cholangitis, psoriasis, psoriatic arthritis, pyoderma gangrenosum, pure red cell aplasia, Raynaud phenomenon, relapsing polychondritis, Reiter's syndrome, restless leg syndrome, retroperitoneal fibrosis, rheumatoid arthritis, rheumatic fever, sarcoidosis, schizophrenia, scleritis, scleroderma, serum sickness, Sjögren's syndrome, spondyloarthropathy, Still's disease, Sweet's syndrome, systemic lupus erythematosus, Takayasu's arteritis, temporal arteritis, thrombocytopenia, transverse myelitis, ulcerative colitis, vasculitis, vitiligo, and Wegener's granulomatosis.
Dependencies are inferred from the claim text.