Blood collection tube, reagent, and method for analyzing blood characteristics using same
AssigneeFujimori Kogyo Co., Ltd.
InventorsKazuya Hosokawa, Tomoko Wada, Hisayo Kaneko, Takaaki Hasegawa, Tomoka Nagasato
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Abstract
A method for analyzing thrombogenic capacity or blood coagulation capacity, the method comprising adding calcium, a blood coagulation factor XII (FXII) inhibitor, and a kallikrein inhibitor to blood collected with a blood collection tube containing sodium citrate, to allow initiation of blood coagulation reaction, is provided. Preferably, heparin, heparan sulfate, and tissue factor are further added to the blood, and thrombogenic capacity or blood coagulation capacity is analyzed.
Claims19
A method for analyzing thrombogenic capacity or blood coagulation capacity, the method comprising adding calcium, a blood coagulation factor XII (FXII) inhibitor, a kallikrein inhibitor, heparin or heparan sulfate, and tissue factor to blood collected with a blood collection tube having a butyl rubber stopper and containing sodium citrate, to allow initiation of a blood coagulation reaction, and then analyzing thrombogenic capacity or blood coagulation capacity using the blood.
A method for analyzing thrombogenic capacity or blood coagulation capacity, the method comprising adding calcium, a blood coagulation factor XII (FXII) inhibitor, a kallikrein inhibitor, and heparin or heparan sulfate to blood collected with a blood collection tube having a butyl rubber stopper and containing sodium citrate, to allow initiation of a blood coagulation reaction, and then analyzing thrombogenic capacity or blood coagulation capacity using the blood, said analysis comprising allowing the blood to flow through a channel(s) mimicking a blood vessel(s) and having a portion coated with collagen and tissue factor provided in a microchip, to analyze mixed white thrombus formation capacity.
A method for analyzing thrombogenic capacity or blood coagulation capacity, the method comprising adding calcium, corn-derived trypsin inhibitor as a blood coagulation factor XII (FXII) inhibitor, aprotinin as a kallikrein inhibitor, heparin or heparan sulfate, and tissue factor to blood collected with a blood collection tube having a butyl rubber stopper and containing sodium citrate, to allow initiation of blood coagulation reaction, and then analyzing thrombogenic capacity or blood coagulation capacity using the blood.
Dependencies are inferred from the claim text.